Research Microscopes
Olympus BX53 - The researchers' choice for quality, performance, and application flexibility.

The new Olympus BX53 provides advanced modularity to suit a variety of observation styles. The rigid, compact space-saving frame features forward-mounted, easy-to-operate controls for improved efficiency and greater operator comfort. New operator controls are accessible from either side of the microscope, and an ECO sensor automatically turns off the transmitted light when the operator is not seated at the microscope. True to the Olympus philosophy, the Olympus BX53 offers an extended range of accessories and objectives to satisfy todays most discerning microscopists.

Key Features:
Suitable for brightfield, darkfield, phase contrast, Nomarski/DIC,polarised light and fluorescence applications
8 Position fluorescence illuminator (accepts CoolLED excitation systems)
Unique Fluorescence Illumination with fly-eye optics
Magnification and filter read-out to cellSens software
Upgradeable with motorised components
Ambidextrous operation
Eco mode

Optically ahead of the curve - the UIS2 optical system
At the heart of any light microscope is the optical system; a series of lenses, prisms and filters designed to magnify the target area of a sample whilst resolving more detail from it. This is far more complex than this basic overview portrays: Since as well as enabling samples to be imaged they allow the introduction and control of light and the projection of images to the eyes (or to a camera). On top of all of this are a range of optical aberrations that can affect microscopy if not properly corrected for. The Olympus UIS2 optical components have been developed to provide the perfect optical system; setting a new standard in precision and clarity.

Dedicated to Fluorescence
As well as the objectives, the new UIS2 fluorescent mirror cube range and 8 position mirror turret have been optimised for flexible and high quality imaging. An ultra high quality coating process provides excellent transmission and exceptionally steep cut-off slopes and the low reflection interior surfaces eliminate over 99% of stray light. As a result, these filter cubes ensure the highest sensitivity  and best colour separation, which coupled with the low auto-fluorescent glass materials, further improves the S:N ratio. In addition the mirror cubes can be exchanged without the need for any tools, making updates very quick and easy.

A novel fluorescence illumination concept
Fluorescence illumination has been at the forefront of life science microscopy for many years. With the BX3 systems, Olympus has incorporated a number of design features and components that will enable fluorescence to maintain this leading position. Of these advances the most important is the introduction of a novel fly-eye lens system which ensures that the field of view is illuminated homogeneously. As well as providing such flawless illumination, the fly-eye system also provides simpler burner alignment.

Ambidextrous
The Olympus BX53 microscope is designed to be ambidextrous so you don’t have to be! For example, the light control dial is placed in the centre of the frame, and the transmitted attenuation filters and fluorescence shutters can be operated from either side, as can the focus knobs. If the microscope is fitted with an Olympus digital camera, a remote exposure button is available, which can also be placed on either side of the frame, enabling uninterrupted image framing and capture. As a result you maintain full control over you workspace, consequently improving workflow efficiency as everything is exactly where you want it.

Motorisation – Pushing the boundaries
The Olympus BX3 microscopes offer even greater application flexibility via a series of motorisation and automation options, all of which can be controlled along with illumination and image capture via the cellSens software. The addition of these motorised and automated components therefore provides excellent potential for enhanced experimentation. The automation options work well in union with each other, but can be implemented as independent solutions, so the user only has to motorise the function(s) they need to. This offers much greater flexibility and cost-efficiency, ensuring that the system is built to the user needs.

Digital imaging ready – uncompromising ergonomics
A range of tubes are available for the BX3 range to suit every requirement. For the greatest system flexibility and user comfort, the tilting, trinocular U-TTR2 tube provides excellent eye piece height adjustment as well as interpupillary distance control, and the optical path slider can be attached to either side of the tube, once again this puts the user in full control of the microscope and ensures that the microscope adjusts to their posture and not vice versa.

Capturing everything correctly – Olympus digital camera range
It is always preferable to have a choice, and this is definitely true when it comes to matching your digital imaging requirements with your project work. For bright-field applications you’ll want dazzling colour fidelity and for fluorescence you’ll need the perfect monochrome capture. There are also those occasions where you would like a microscope camera that can do both. Add to this selection the ability to pick from a range of image sizes and resolutions, and the Olympus digital microscope camera range really does offer you the flexibility of choice. 

Total system control – cellSens software for life science applications
Consisting of three different packages: cellSens Entry, cellSens Standard and cellSens Dimension, all user requirements can be met with ease. Incorporating a unique user-definable interface, the imaging process can be personalised from start to finish, for complete control over the entire experiment. Furthermore, each package integrates seamlessly with Microsoft Windows and Office programmes, making the advanced functionality of the Olympus cellSens family extremely user-friendly. 
Published in Olympus Microscopes
The automated microscope system for high-end fluorescence imaging.

Key Features:
Most accurate motorised Z-drive
Highest stability due to fixed stage design
Highly precise ultra-sonic stage
Unique operational concept
Unmatched workspace personalisation
Full control via touch panel controller
Detachable manual controller
Intuitive contrast management
Compatible with CoolLED fluorescence excitation systems

The Olympus BX63 is completely motorised and is uniquely focused via the nosepiece rather than stage, which enables the stage to be fixed making it more stable. The motorised stage is also new and is driven by advanced, high precision, ultrasonic Piezo technology, providing silent, smooth and extremely precise operation. The stage can even be positioned by hand enabling rapid gross sample alignment while highly accurate encoders continuously read-out X,Y position The excellent encoding enables the user to set precise coordinates and navigate directly to them at high speed.

Be precise! – Ultrasonic motorised stage
The Olympus BX63 features a new, highly accurate, ultrasonic stage. Driven by advanced Piezo technology, the stage has a small form factor with silent and extremely smooth operation. It can also be physically positioned by hand enabling rapid gross sample alignment. Via the high precision built-in encoders, the stage provides true X,Y coordination, enabling the user to set exact coordinates and navigate directly to them at high speed, even if the stage has been manually positioned. This new ultrasonic stage is also the basis for the automation of complex imaging procedures, such as MIA and multi-dimensional experiments, using the cellSens software packages.

Design your personal workspace – Unique control concept
Every person has a different way of organising their things – be it their work desk or their wardrobe, and their way will not necessarily suit anyone else. Olympus has enabled this complete user-defined control concept with its BX63 microscope, which combines detachable manual controllers, touch panel and software control and allows unmatched workspace personalisation.

Control at your fingertips – The BX63 touch panel
The BX63 is supplied with a unique, programmable touch-screen control that greatly simplifies observation and imaging tasks and offers full control of all microscope functions including focus and motorised stage. The interface can be set to a ‘navigation mode’ that is context-sensitive, displaying only the functions that are relevant to observation method in use. The alternative ‘full operation’ mode allows researchers access to the full range of functions and customisation options available. The user account system provides more than 30 individual accounts, which can be used for personal settings and can all be protected by password.

The manual touch – detachable control units
For users that prefer hands-on control, the BX63 has an optional remote control unit that can be placed wherever the user requires it. For more traditional working the controls can be affixed to the front of the frame. This unit provides coarse and fine focus knobs, X,Y stage controller and push button controls for efficiently changing between observation methods, objectives and mirror units, as well as for adjusting light intensity and controlling camera and fluorescence shutter.

Total system control – cellSens software for life science applications
Consisting of three different packages: cellSens Entry, cellSens Standard and cellSens Dimension, all user requirements can be met with ease. Incorporating a unique user-definable interface, the imaging process can be personalised from start to finish, for complete control over the entire experiment. Furthermore, each package integrates seamlessly with Microsoft Windows and Office programmes, making the advanced functionality of the Olympus cellSens family extremely user-friendly.

Optically ahead of the curve – the UIS2 optical system
At the heart of any light microscope is the optical system; a series of lenses, prisms and filters designed to magnify the target area of a sample whilst resolving more detail from it. This is far more complex than this basic overview portrays: Since as well as enabling samples to be imaged they allow the introduction and control of light and the projection of images to the eyes (or to a camera). On top of all of this are a range of optical aberrations that can affect microscopy if not properly corrected for. The Olympus UIS2 optical components have been developed to provide the perfect optical system; setting a new standard in precision and clarity.

Dedicated to Fluorescence
As well as the objectives, the new UIS2 fluorescent mirror cube range and 8 position mirror turret have been optimised for flexible and high quality imaging. An ultra high quality coating process provides excellent transmission and exceptionally steep cut-off slopes and the low reflection interior surfaces eliminate over 99% of stray light. As a result, these filter cubes ensure the highest sensitivity  and best colour separation, which coupled with the low auto-fluorescent glass materials, further improves the S:N ratio. In addition the mirror cubes can be exchanged without the need for any tools, making updates very quick and easy.

A novel fluorescence illumination concept
Fluorescence illumination has been at the forefront of life science microscopy for many years. With the BX3 systems, Olympus has incorporated a number of design features and components that will enable fluorescence to maintain this leading position. Of these advances the most important is the introduction of a novel fly-eye lens system which ensures that the field of view is illuminated homogeneously. As well as providing such flawless illumination, the fly-eye system also provides simpler burner alignment.

Digital imaging ready – uncompromising ergonomics
A range of tubes are available for the BX3 range to suit every requirement. For the greatest system flexibility and user comfort, the tilting, trinocular U-TTR2 tube provides excellent eye piece height adjustment as well as interpupillary distance control, and the optical path slider can be attached to either side of the tube, once again this puts the user in full control of the microscope and ensures that the microscope adjusts to their posture and not vice versa.

Capturing everything correctly – Olympus digital camera range
It is always preferable to have a choice, and this is definitely true when it comes to matching your digital imaging requirements with your project work. For bright-field applications you’ll want dazzling colour fidelity and for fluorescence you’ll need the perfect monochrome capture. There are also those occasions where you would like a microscope camera that can do both. Add to this selection the ability to pick from a range of image sizes and resolutions, and the Olympus digital microscope camera range really does offer you the flexibility of choice.
Published in Olympus Microscopes
Olympus IX71 for versatile routine work and research

Key Features:
Improved fluorescence illuminator, CoolLED compatible
V-shaped optical path for brighter primary images
Exceptional ease of use and comfort
System versatility

The Olympus IX71 is an advanced inverted microscope system for cell imaging, the Olympus IX71 has a unique two-tiered multi-port design for maximum flexibility. Superb fluorescence, DIC, phase contrast and Olympus Relief Contrast modes are available. The microscope sets new standards in inverted microscopy with its stable compact frame and outstanding optical performance.

UIS2 - making the invisible visible
The new milestone in optical evolution - UIS2.  See what you never saw before and protect your cells against harmful radiation. Superb signal to noise performance and enhanced spectral range deliver maximum signal with minimum excitation power. And the once more improved chromatic aberration correction guarantees highest colour fidelity.

Slim and Rigid
Reduced to the Max without any compromise for stability. The IX2 inverted research frames are unsurpassed in compactness with concurrent rocklike stability.

Multiport Concept
No other microscope system offers you greater flexibility. The IX71/IX81 frames are equipped with several illumination and detection ports, with your specific port configurations for each microscope being possible.
 
Fluorescence
Olympus fluorescence illumination combined with Olympus high definition ion coated filters. Highest signal to noise performance incorporating the wavelength accuracy, edge steepness and low autofluorescence of the UIS2 HQ-fluorescence-filters offer the potential for new discoveries. Innovative fluorescence detection methods like total internal reflection fluorescence (TIRF) and the disc scanning confocal unit (DSU) expand your view to surface phenomena (TIRF) and produce life 3D images (DSU).

Contrast tailored to your needs
With the flexible and new UIS2 DIC system you can adjust the contrast to your needs. From thin to thick specimen you will surely find the right contrast in every required magnification. The Olympus Relief Contrast delivers clear 3D-like images for accurate and easy manipulation across all magnifications with optimised visualisation of cellular membranes.

Modular Motorisation
Motorisation is essential for full process automation. The Olympus modular motorisation concept allows you to choose the automation level depending on your requirements. Motorised modules for IX81 and the manual IX51/71microscopes include fluorescence and transmitted light condensers, filterwheels for illumination and observation light paths, shutters and stages. Everything controlled by a convenient hand switch or by our imaging software.

System Solutions
No matter if you just would like to archive your images, analyse multistained specimens or run automated experiments etc., the familiy of Olympus Imaging software packages has the right solution ready for you. From basic packages up to highly integrated solutions for imaging, microdissection, high content screening and more. Our field- and in-house specialists support you in finding the best solution.
Published in Olympus Microscopes
Olympus IX81 - for fully motorised advanced microscopy

Key Features:
Flexible platform for automated solutions
Fully automated platform for live cell imaging
Primary images can be obtained from all four camera ports simultaneously
Complete customisation for individual needs
Accepts CoolLED fluorescence excitation modules
Independent motorised units
Provided with powerful software

The Olympus IX81 provides the highest standards of observation and functional operation as well as the performance required for accurate research applications. The motorised system has the flexibility to be readily adapted to different research purposes and provides excellent performance in imaging, analysis and manipulation. Applications include brightfield, phase contrast, Nomarski/DIC and fluorescence.

UIS2 - making the invisible visible
The new milestone in optical evolution - UIS2.  See what you never saw before and protect your cells against harmful radiation. Superb signal to noise performance and enhanced spectral range deliver maximum signal with minimum excitation power. And the once more improved chromatic aberration correction guarantees highest colour fidelity.

Slim and Rigid
Reduced to the Max without any compromise for stability. The IX2 inverted research frames are unsurpassed in compactness with concurrent rocklike stability.

Multiport Concept
No other microscope system offers you greater flexibility. The IX71/IX81 frames are equipped with several illumination and detection ports, with your specific port configurations for each microscope being possible.
 
Fluorescence
Olympus fluorescence illumination combined with Olympus high definition ion coated filters. Highest signal to noise performance incorporating the wavelength accuracy, edge steepness and low autofluorescence of the UIS2 HQ-fluorescence-filters offer the potential for new discoveries. Innovative fluorescence detection methods like total internal reflection fluorescence (TIRF) and the disc scanning confocal unit (DSU) expand your view to surface phenomena (TIRF) and produce life 3D images (DSU).

Contrast tailored to your needs
With the flexible and new UIS2 DIC system you can adjust the contrast to your needs. From thin to thick specimen you will surely find the right contrast in every required magnification. The Olympus Relief Contrast delivers clear 3D-like images for accurate and easy manipulation across all magnifications with optimised visualisation of cellular membranes.

Modular Motorisation
Motorisation is essential for full process automation. The Olympus modular motorisation concept allows you to choose the automation level depending on your requirements. Motorised modules for IX81 and the manual IX51/71microscopes include fluorescence and transmitted light condensers, filterwheels for illumination and observation light paths, shutters and stages. Everything controlled by a convenient hand switch or by our imaging software.

System Solutions
No matter if you just would like to archive your images, analyse multistained specimens or run automated experiments etc., the familiy of Olympus Imaging software packages has the right solution ready for you. From basic packages up to highly integrated solutions for imaging, microdissection, high content screening and more. Our field- and in-house specialists support you in finding the best solution.
Published in Olympus Microscopes
Key Features
Flexible platform for automated solutions
Integrated laser-based Z-drift compensation system
Continuous and ‘One-shot’ drift compensation mode
Compatable with CoolLED fluorescence excitation systems
Independent motorised units
Provided with powerful software

Z-Drift Compensation – keeping your research in focus
The new laser-based Z-drift compensator (ZDC2) ensures that your samples are always in focus, providing the sharpest images possible. The system features two working modes – continuous and ‘one-shot’ which enable the completion of any time-lapse experiments. The ZDC2 continually monitors the distance between the objective lens and the sample surface, thus maintaining accurate focus during even the fastest time-lapse experiments. In contrast, the ‘one-shot’ mode facilitates applications requiring multiple focal positions. Providing superior speed, accuracy and flexibility, the ZDC2 Z-Drift compensation microscope system is perfect for any live-cell imaging, maintaining optimal focus image after image, regardless of experiment length or complexity.

UIS2 - making the invisible visible
The new milestone in optical evolution - UIS2. See what you never saw before and protect your cells against harmful radiation. Superb signal to noise performance and enhanced spectral range deliver maximum signal with minimum excitation power. And the once more improved chromatic aberration correction guarantees highest colour fidelity.

Slim and Rigid
Reduced to the Max without any compromise for stability. The IX2 inverted research frames are unsurpassed in compactness with concurrent rocklike stability.

Fluorescence
Olympus fluorescence illumination combined with Olympus high definition ion coated filters. Highest signal to noise performance incorporating the wavelength accuracy, edge steepness and low autofluorescence of the UIS2 HQ-fluorescence-filters offer the potential for new discoveries. Innovative fluorescence detection methods like total internal reflection fluorescence (TIRF) and the disc scanning confocal unit (DSU) expand your view to surface phenomena (TIRF) and produce life 3D images (DSU).

Modular Motorisation
Motorisation is essential for full process automation. The Olympus modular motorisation concept allows you to choose the automation level depending on your requirements. The fully automatable IX81 comes with integrated motorised high-precision Z-drive, motorised nosepiece, motorised lightpath changer and programmable frame keys. Motorised modules for IX81 and the manual IX51/71microscopes include fluorescence and transmitted light condensers, filterwheels for illumination and observation light paths, shutters and stages. Everything controlled by a convenient hand switch or by our imaging software.

System Solutions
No matter if you just would like to archive your images, analyse multistained specimens or run automated experiments etc., the family of Olympus Imaging software packages has the right solution ready for you. From basic packages up to highly integrated solutions for imaging, microdissection, high content screening and more. Our field- and in-house specialists support you in finding the best solution.
Published in Olympus Microscopes